BK Virus

BKV Screening

  • Screening for viremia should occur at 1, 2, 3, 4, 5, 6, 9 and 12 months post-renal transplantation.
  • Thereafter, screening should be every 3 months in year 2 and every 6 months in years 3-5 (i.e. a total of 5-year surveillance).
  • The laboratory will not process a request if <4 weeks has elapsed since the previous result (unless that sample had a positive result).
  • In the event of a first positive result, a follow up test in <4 weeks (but not < than 2 weeks) is warranted. In this instance, it should be specified on the clinical information that this is a follow up of a positive result to ensure the request is processed.

Management of BK Viremia (+/- BK Nephropathy)

Reduction in immunosuppression is the cornerstone of BKV management. A useful algorithm for the approach after a positive result is provided below.

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