Hepatitis B Immunisation- HBVaxPro
|Indication||Immunisation against hepatitis B infection in all patients starting haemodialysis.|
|Dosage and administration||40 micrograms at 0, 1 and 6 months by IM injection
Patients should be regarded as a ‘responder’ if anti HBs antibody titre is >100mIU/ml 8 weeks after completing immunisation. Responders should have an annual anti HB antibody titre check and a booster given if level <100mIu/ml.
If level 10-100mIU/ml- give booster and recheck after 4-8 weeks.
If level <10mIU/ml- course repeated once and recheck at 6-8 weeks. If still <10mIU/ml, then patient is a ‘non responder’.
If level 10-100mIU/ml then give booster.
|Side effects||Hypotension – monitor BP throughout infusion. Usually only predicted following rapid infusion of large doses and should be self-limited and transient.
Nausea & vomiting – give ondansetron as above. Continued nausea may require infusion being given over a longer period of time (e.g. over full dialysis session) or dose reduction.
Other reported side effects (from case reports):
|Additional information||Store in a refrigerator
Not to be injected into the buttock (vaccine efficacy reduced).
Other preparations available if supply issues with HBVaxPro: