{"id":1536,"date":"2018-09-12T11:25:50","date_gmt":"2018-09-12T11:25:50","guid":{"rendered":"http:\/\/edren.org\/ren\/?page_id=1536"},"modified":"2025-03-25T16:36:08","modified_gmt":"2025-03-25T16:36:08","slug":"management-of-delayed-graft-function","status":"publish","type":"page","link":"https:\/\/edren.org\/ren\/handbook\/transplant-handbook\/management-of-delayed-graft-function\/","title":{"rendered":"Management of delayed graft function"},"content":{"rendered":"<p>Not all kidneys function immediately and some take a few days or even weeks before functioning.\u00a0 During this time the aim is to ensure that we are not missing concomitant rejection or other reversible injury during this time.<\/p>\n<table style=\"width: 95%; border-collapse: collapse;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 17.1395%; background-color: #e6f7ed; border-color: #993300; border-style: solid;\"><strong><span style=\"font-family: georgia, palatino, serif; color: #993300;\">Day 1<\/span><\/strong><\/td>\n<td style=\"width: 93.6589%; border-color: #993300; border-style: solid;\">\n<ul style=\"list-style-type: disc;\">\n<li><span style=\"font-family: georgia, palatino, serif;\">Duplex scan<\/span><\/li>\n<li><span style=\"font-family: georgia, palatino, serif;\">Routine immunosuppression. Aim for low level of tacrolimus (5-7) if low immunological risk.<\/span><\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 17.1395%; background-color: #e6f7ed; border-color: #993300; border-style: solid;\"><strong><span style=\"color: #993300;\">Day 5<\/span><\/strong><\/td>\n<td style=\"width: 93.6589%; border-color: #993300; border-style: solid;\">\n<ul style=\"list-style-type: disc;\">\n<li><span style=\"font-size: 14pt;\">If no evidence of improvement then biopsy to exclude rejection.<\/span><\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 17.1395%; background-color: #e6f7ed; vertical-align: middle; border-style: solid; border-color: #993300;\"><strong><span style=\"color: #993300;\">Day 10 &#8211; 12<\/span><\/strong><\/td>\n<td style=\"width: 93.6589%; border-style: solid; border-color: #993300;\">Repeat Duplex\/biopsy.<\/p>\n<p>Treat rejection as per protocol (page 27-28)<\/p>\n<ul style=\"list-style-type: disc;\">\n<li>In cases of prolonged delayed graft function, additional biopsies may be required.<\/li>\n<li>If haemodialysis is required, NO ANTICOAGULATION must be used during the first post-operative week.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Not all kidneys function immediately and some take a few days or even weeks before functioning.\u00a0 During this time the aim is to ensure that we are not missing concomitant rejection or other reversible injury during this time. Day 1 Duplex scan Routine immunosuppression. Aim for low level of tacrolimus\u2026<\/p>\n<p> <a class=\"continue-reading-link\" href=\"https:\/\/edren.org\/ren\/handbook\/transplant-handbook\/management-of-delayed-graft-function\/\"><span>Continue reading<\/span><i class=\"crycon-right-dir\"><\/i><\/a> <\/p>\n","protected":false},"author":2,"featured_media":0,"parent":1453,"menu_order":195,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"class_list":["post-1536","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/edren.org\/ren\/wp-json\/wp\/v2\/pages\/1536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/edren.org\/ren\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/edren.org\/ren\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/edren.org\/ren\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/edren.org\/ren\/wp-json\/wp\/v2\/comments?post=1536"}],"version-history":[{"count":4,"href":"https:\/\/edren.org\/ren\/wp-json\/wp\/v2\/pages\/1536\/revisions"}],"predecessor-version":[{"id":1542,"href":"https:\/\/edren.org\/ren\/wp-json\/wp\/v2\/pages\/1536\/revisions\/1542"}],"up":[{"embeddable":true,"href":"https:\/\/edren.org\/ren\/wp-json\/wp\/v2\/pages\/1453"}],"wp:attachment":[{"href":"https:\/\/edren.org\/ren\/wp-json\/wp\/v2\/media?parent=1536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}