Rhesus negative female recipients


Rh -ve female recipients aged <50 years with Rh +ve donor require anti-D immunoglobulin at induction (can be given up to 72 hours later if necessary).

  • A dose of at least 500iu should given via IM injection.
  • In practice, at RIE, the available dose is likely to be 1500iu.
  • SNBTS policy suggests flow cytometry at 72 hours post dose to check all D-antigens have been neutralised but if the 1500iu dose has been given this will not be necessary.